Rau 30th, Yokohama Rubber Co., Ltd. tshaj tawm tias nws tau tsim lub "ntiaj teb thawj" cov cuab yeej siv los tsim cov isoprene los ntawm biomass (isoprene yog ib yam khoom raw rau cov khoom siv hluavtaws roj hmab), thiab lub tuam txhab tseem hais tias Lub tshuab no kuj raug siv rau kev siv ntawm butadiene hluavtaws roj hmab raws li lwm cov diene rubbers.
Xyoo 2013, Yokohama Rubber thiab Riken Research thiab Ryan Chemical pib kawm, siv cov txheej txheem tsim qauv siv computer los ntawm metabolic mus tshawb nrhiav cov txheej txheem tshiab yogoprene synthesis ua ntej ob xyoos.
Yokohama tau hais tias peb lub tog neeg tau tsim dua tshiab cov kev siv tshuab tshiab, raws li lub tshuab muaj zog tshaj plaws uas tsim los ntawm nws, uas tau tsim cov hlwb nrog "zoo tshaj isoprene synthesis", uas tau raug tsim los ntawm lub cev. Lub peev xwm ntawm ib yam khoom (feem ntau yog qab zib) tsim cov isoprene rau polymerize isoprene uas ua rau hauv ib lub xovtooj ntawm tes, ua li no paub qhov hluav taws xob ntawm cov roj hmab polyisoprene.
Yokohama ntxiv hais tias isoprene feem ntau xav tias yuav ua los ntawm pentanoic acid, ib nrab ua tau los ntawm suab thaj, los ntawm kev sib tsib theem, tab sis nws cov khoom siv dag zog tshiab uas tsim los ntawm kev sib koom tes sib koom tes yuav txo cov txheej txheem no rau ob. ntu.
Lub tuam txhab tseem hais tias qhov no ua kom nquag enzyme muaj peev xwm ua kom muaj cov isoprene uas tsis muaj peev xwm ua tau nrog cov ntuj tsim teb raug. Thaum qhia cov enzymes hauv E. coli, cov kab mob muaj peev xwm tsim cov isoprene. Isoprene yog tam sim no ua feem ntawm thermal cracking ntawm naphtha.